Thermoshake AC LC
Precise heating, cooling & shaking in one small device
Save precious deck space with one device that delivers accurate heating, cooling and rapid shaking of up to 1 kg loads.Combined heater/coolers and shakers add efficiency and precision to liquid handling decks for many life science research applications in molecular biology, biochemistry and clinical chemistry. They give labs more control of the process, and that helps achieve more accurate and repeatable results. And by reducing reaction process times and lessening operator workload they can help increase lab throughput.
Thanks to its automated clamping technology the Thermoshake AC LC can handle loads of up to 1 kg with rapid shaking at up to 3,000 rmp.
Combined heater/coolers and shakers can be problematic when working without on-deck air-conditioning. Labs report problems with on-deck waste heat that increases the ambient temperature of the deck, air movement from fans increases the risk of sample cross-contamination, and there’s excessive noise when many devices work together. Cold plate liquid cooling moves heat dispersal off deck and can solve those problems.
OFF DECK LIQUID COOLING
The Thermoshake AC LC replaces the usual on-deck heat sink/fan combination with liquid heat exchangers and transfer heat to the environment via a heat exchanger outside the deck. For fast heating and cooling steps that require high precision there’s less risk of disturbance or contamination from waste heat generation or air movement from fans.
UNIFORMITY AND ACCURACY
The Thermoshake AC LC gives you precise control over sample processing. Define set temperatures with a temperature range of
4 °C to 70 °C and a uniformity and accuracy of 0.3 K. Choose the orbital shaking frequency, from 200 to 3,000 rpm. For every temperature and every frequency, you’ll get uniform and accurate processing for every sample.
ADAPTABLE
Use your preferred disposable with the Thermoshake AC LC Active clamping (automated labware clamping), using customized clamping rods for different labware, lets you use different format plates without adjustment. That also enables you to shake plates with clamped lids and allows piercing through sealing foils while keeping the plate firmly clamped. We offer over 200 adapters, manufactured in-house to ensure a perfect fit to the geometry of the disposable item, or can tailor an adapter to fit your needs.
EASY TO INTEGRATE
The Thermoshake AC LC has a small footprint
(104 mm W x 147 mm D x 97 mm H), zero positioning function for comfortable robotic gripping, and it’s integrated with all major deck manufacturers enabling immediate plug-and-play. API available.
RELIABLE AND SUPPORTED
Every Inheco device is designed, engineered and made in Germany and undergoes rigorous quality control before delivery. It comes with a global two-year warranty and full customer service including remote support, diagnostic and servicing options that focusses on minimizing operational downtime.
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Brochure (PDF)
Thermoshake AC LC (PDF)
CPLC Ultraflat MTC Manual (PDF)
Manual Heat Exchanger (PDF)
Production Facility Inspection (PDF)
EC Decaration (PDF)
Technical Specifications Thermoshake AC LC
| Thermoshake AC LC | |
|---|---|
| Product number | p/n 7100170 |
| Height (bottom to contact surface) | 90.6mm [3.567in] |
| Height with standard fixation pins | 96.9mm [3.814in] |
| Length x width | 147 mm x 104 mm [5.787 in x 4.095 in] |
| Temperature range | +4 °C to +70 °C [+39.2 °F to +158 °F] |
| Maximum temperature difference in cooling mode ∆T (=Tambient- Ttarget) |
25 K |
| Noise | Max. 42 dB(A) |
| Protection category | IP 20 |
| Weight including cables | 3.8kg [8.4lbs] |
| Technical information regarding shaking for all devices | |
|---|---|
| Maximum load | 1.0kg [2.2lbs] |
| Shaker frequency weight reduce the max. speed | 300 to 3000 rpm* |
| Shaking amplitude | 2 mm [0.07874 in] |
| Shaking pattern | Orbital |
* Depending on the load, as otherwise liquid might get spilled or adapter might not be hold tight to the clamp mechanism. We recommend to test the speed you want to use with a microtiter plate and water to test the behavior first.
| Environmental conditions | |
|---|---|
| Tolerable relative humidity: | |
| Operation | 10-80% RH *3 (non condensing) |
| Transportation and storage | 10-80% RH *3 (non condensing) |
| Temperature: | |
| Operation | +15 °C to +32 °C [+59 °F to 90 °F] |
| Transportation and storage | -10 °C to +60 °C [+14 °F to 140 °F], *3 non condensing |
*3) Condensate can prevent the Shaking devices from operating properly and can damage the Thermoshake AC. Condensate should be eliminated on a daily basis or more often, for example by heating cycles in between cooling cycles.
Thermoshake AC LC Accessories
Why use a combined thermoshaker?
Heating, cooling and maintaining ambient temperatures, while shaking, are fundamental to many life sciences processes carried out in an automated liquid handling deck. When on deck space is at a premium, it makes sense to use one multi-functional combined device – but only when you can be sure performance won’t be compromised.What to look for in a combined thermoshaker?
Accurate uniform heating, cooling and shaking for every sample are the prerequisites for thermoshakers. That means ensuring that your samples are safely clamped during the shaking, and that they all reach the same temperature for the same amount of time.
- Temperature uniformity – delivering identical temperature across the entire block, with identical results for samples in the middle or on the edge of the block, and throughout the run.
- Temperature accuracy – ensuring accurate and stable, reproduceable temperatures for the duration of the run, and for every sample in the block.
- Uniform temperature change (ramp rates) – maintaining temperature uniformity across the entire block.
- Shaking options – both speed and pattern (for linear shaking, see our Thermoshake Classic).
- Load – handling the heaviest load you are likely to require.
- Secure grip on disposable while shaking.
- Small footprint – delivering the required performance while taking up as little space on deck as possible.
Use of the Inheco Thermoshake AC LC
The Thermoshake AC LC is in regular use in NGS Sample Prep.In bead extraction, when lysis is performed with higher temperature and the next steps require RT processing. The Thermoshake AC LC’s higher shaking with higher load allows magnetic bead extraction of "heavy bead" even in larger disposables.
The Thermoshake AC LC can also be used to keep samples at room temperature during shaking.
Shaking
The Thermoshake AC LC shakes using an electromagnetic motor
The Thermoshake AC LC heats and cools using a Peltier unit and prevents self-heating at ambient incubation to allow the cooling function to operate.
The Thermoshake AC LC shakes using an electromagnetic motor
- Orbital shaking pattern
- 200 - 3,000 rpm
- 2 mm amplitude
- Anti-spillage
- Anti-vibration
The Thermoshake AC LC heats and cools using a Peltier unit and prevents self-heating at ambient incubation to allow the cooling function to operate.
- Peltier Modules or Thermoelectric Coolers (TECs) use the Peltier effect to create a heat flux between the junction of two different types of materials. A Peltier cooler, heater, or thermoelectric heat pump is a solid-state active heat pump which transfers heat from one side of the device to the other side against the temperature gradient (from cold to hot), with consumption of electrical energy. TECs run with DC voltage, and it’s easy to control the heat transfer through the module by changing the current. When the polarity of the DC is switched, the TEC swaps from cooling to heating mode. That makes TECs an excellent solution when exact control of temperature and heating and cooling rates are needed.
- Temperature range: +4 °C to +70 °C
- From 20 °C to 68 °C in 300 sec, or 9 °C per minute heating rate (to ensure precise temperatures)
- From 70 °C to 25 °C in 450 sec, or 6 °C per minute cooling down
- Optimized temperature control to avoid overshooting or undershooting of target temperature
Liquid cooling
- The Thermoshake AC LC uses an off-deck liquid heat exchanger to remove waste heat.
- API available. The INHECO Thermoshake AC LC is quick to connect, and ready for future developments in your lab.